NeuroTester Air

A simple system for Cardiac Autonomic Neuropathy screening

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Cardiovascular tests to diagnose Diabetic Autonomic Neuropathy

The longer diabetes persists, the greater the risk of developing Cardiac Autonomic Neuropathy (CAN), which is today one of the most threatening complications that may occur concomitantly with Diabetes Mellitus. It is fundamental to prevent or identify CAN at the subclinical stage, when the condition is still reversible. NeuroTester is the most popular device to conduct Cardiovascular reflex tests.

Quick Overview on NeuroTester Air

Watch the video

Verbal commands, very simple!

By simultaneously measuring heart rate with respiratory rate, intrathoracic pressure and orthostatic blood pressure, these tests evaluate variations in heart rate during deep breathing (Deep Breathing), after postural change from clinostatism to orthostatism (Lying to Standing), and during forceful attempted expiration against a closed airway (Valsalva Maneuver).

In-depth look


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The NEW NeuroTester Air is a medical device for the evaluation of the cardiovascular reflex response and, in turn, of changes in the autonomic nervous system, which may occur concomitantly with diabetes. These screening tests may indicate the need for more complex diagnostic evaluation by Diabetologists and trained nursing staff.

This device allows cardiovascular tests to be performed without using an electrocardiograph. The System monitors simultaneously: heart and respiratory rate (Deep Breathing test), intrathoracic pressure (Valsalva Maneuver), and orthostatic blood pressure (Lying to Standing test).

The New NeuroTester Air does not require the patient to undress, thanks to its innovative capacitive ECG sensors positioned on the patient’s wrists, which replace the less practical chest electrodes, thereby vastly reducing test preparation times. A voice assistant walks the patient through each test step specifying the actions to be taken. An intelligent mouthpiece records the respiratory flow by way of an internal pressure sensor, which reads the pressure produced by the patient’s breathing into the mouthpiece. An integrated accelerometer in the base unit placed on the patient’s thigh, automatically detects the patient’s lying or standing position. After each test, NeuroTester Air automatically calculates results, displaying normal parameters values in relation to the patient’s reference values. Relying upon Bluetooth technology, NeuroTester Air communicates with software interface that allows the operator to view all parameters during testing. In addition to promoting a more fluid use of the device, real-time wireless transmission also reduces cable clutter and allows the test subject greater freedom of movement during the test. Furthermore, we have formulated an accurate, innovative system to validate the quality of test execution, by monitoring simultaneously heart rate and the second parameter that causes variations in heart rate. In addition, the NeuroTester Air automatically detects extrasystoles on the basis of changes in the QRS complex, and excluding them for test results. However, by delving more in-depth into an analysis of parameters, the operator may, at any time and at his discretion, select different elements to evaluate, even including or excluding heart beats the system has identified as conditions or suspected atrial/ventricular extrasystoles. NeuroTester Air was designed to operate without a connection to a power grid. The built-in lithium battery allows the device to operate for long periods of time, as well as maximum portability offering considerably more flexibility than its predecessor.